United States · FDA National Drug Code directory

Severe cold and flu Nighttime

A source-listed medicine record.

Factual source checks only. This page is not a clinically reviewed monograph. Historical or discontinued records may be included; listing does not confirm approval, current availability or pharmacy stock.

Medicine identity

Source reference: 49580-0416_46f4b7c3-c197-4717-8036-499652b0d716
Product NDC: 49580-0416
Form: LIQUID
Composition / generic term: Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine Succinate, Phenylephrine HCI
Labeler: P & L Development, LLC
Marketing category: OTC MONOGRAPH DRUG
Marketing start / end (source format): 20150831
Source listing expiry: 20261231

Source-listed ingredients

ACETAMINOPHEN — 650 mg/30mL
DEXTROMETHORPHAN HYDROBROMIDE — 20 mg/30mL
DOXYLAMINE SUCCINATE — 12.5 mg/30mL
PHENYLEPHRINE HYDROCHLORIDE — 10 mg/30mL

These values do not establish equivalence or a dose recommendation.

Packages

237 mL in 1 BOTTLE, PLASTIC (49580-0416-8) · 49580-0416-8

Source and coverage

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Snapshot retrieved: 2026-09-17. This is the acquisition date, not a medical review date.

Clinical information, images and comparisons appear only when separately reviewed for this record. Coverage may be incomplete. Ask a pharmacist or clinician about your treatment.

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